After traditional glaucoma surgery (called trabeculectomy),
Zenith Labs Vision 20 Review scarring is every surgeon's nightmare. The tract the surgeon has created to let fluid out of the eye is at risk of closing if scarring ensues. Wound healing therefore defeats the whole purpose of the glaucoma surgery, which is to relieve the pressure of the accumulating fluid inside the eyeball.
The quest for a safer drug to halt scarring it, therefore, the holy grail of trabeculectomy surgery. Initial studies of the steroid triamcinolone suggest that it could be an effective alternative to 5-FU and MMC in post-operative control of inflammation and scarring. Although triamcinolone has long been used for various allergies of the body like asthma and other inflammatory conditions like arthritis, its potency in controlling ocular healing after trabeculectomy has only been recently been shown. In one study close to 93% of patients receiving triamcinolone injections after trabeculectomy had normal eye pressures after six months of treatment.
Another advantage of triamcinolone over traditional antimetabolites is its non-traumatic delivery. Since it is not injected directly in the surgical site, it prevents accidental piercing of the artificially created pocket (bleb) where the fluid drains.There are, however, alternatives to bleb-dependent surgeries such as trabeculectomy. With Canaloplasty, for example, the success of glaucoma surgery does not depend on wound modulating agents like triamcinolone. In fact, with Canaloplasty it is perfectly fine for the body to scar down as it normally would. Rather than fight the body's natural tendency to heal, Canaloplasty simply opens the natural drainage channels already present in the eye.
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